It becomes a new weapon against rheumatism.
To date, the exact pathogenesis of RA remains uncertain. Some patients with severe disease may not have a satisfactory treatment effect even after routine treatment.
Although glucocorticoid hormones and cytostatics are the main weapons for most rheumatoid arthritis, their effects on severe lupus, systemic sclerosis, and refractory rheumatoid arthritis are not very satisfactory.
In general, if patients with very fatal rheumatoid arthritis are not effective after routine treatment, they can all receive a hematopoietic stem cell transplant (HSCT) as long as they do not show irreparable organic damage.
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HSCT hematopoietic stem cell transplant can treat systemic lupus erythematosus (SLE), rheumatoid arthritis, systemic sclerosis, antiphospholipid antibody syndrome, necrotizing vasculitis, myositis, dermatomyositis, psoriasis.
The Effects of hematopoietic stem cell transplantation on rheumatoid disease.
HSCT has different effects and different levels of safety in different autoimmune diseases, depending on the subject, the patient's case choice, and the method of prevention.
Usually, surprisingly, transplant-related mortality was the highest and the best effect on rheumatoid arthritis (RA), especially in adolescent RA patients.
In 2003, transplant-related mortality from rheumatoid arthritis was lowest among 400 cases in European patients, including rheumatoid arthritis (RA), systemic lupus erythematosus, systemic sclerosis and juvenile idiopathic arthritis, accounting for only 1.4% and other diseases higher than 10%, which may be associated with organ damage due to other diseases.